Ajax have been hit by the news striker Bojan Krkic has been ruled out for up to six weeks with a hamstring injury.
Sebastian Vettel has taken another big step towards a fourth successive title by claiming pole for the Italian GP.
FC Twente moved to the top of the Eredivisie by thumping 10-man Groningen 5-0, while Heerenveen beat Cambuur Leeuwarden.
AZ Alkmaar have confirmed the shock departure of coach Gertjan Verbeek - despite overseeing victory over PSV Eindhoven.
PSV Eindhoven slipped to their first Eredivisie defeat of the season at AZ Alkmaar, while Ajax thrashed Go Ahead Eagles.
Heerenveen moved into the third round of the KNVB Beker with an emphatic 3-0 defeat of 10-man FC Twente.
Holders AZ Alkmaar and 18-time winners Ajax survived scares to progress in the KNVB Beker with 4-1 and 4-2 wins.
NEC Nijmegen took out their league frustrations on minnows Harkemase Boys in the KNVB Beker with an 8-0 mauling.